Klotho Peptide Fragment

Category: Longevity & Anti-Aging

A bioactive peptide fragment derived from the Klotho protein — a potent anti-aging longevity gene product. Klotho deficiency is associated with accelerated aging, cognitive decline, kidney disease, and cardiovascular dysfunction. Klotho peptide fragments (particularly those mimicking the KL1 domain) are being researched for their ability to improve cognition, protect the kidneys, reduce systemic inflammation, and extend healthspan.

Half-Life: 8 hours

Common Dosage: 0.1–0.5mg

Benefits

  • Neuroprotective effects — improves memory and cognitive function
  • Kidney protection and anti-fibrotic effects
  • Cardiovascular protection
  • Reduces systemic inflammation
  • Potential extension of healthspan
  • Antioxidant activity
  • Improves synaptic plasticity and NMDA receptor function

Side Effects

  • Research compound with limited human safety data
  • Injection site reactions
  • Mild fatigue on initiation (anecdotal)
  • Headache (rare)