MOTS-c + SS-31 Stack

Category: Mitochondrial Longevity Stack

A powerful mitochondrial optimization stack combining MOTS-c (a mitochondrial-derived peptide that regulates metabolic function and mimics exercise effects) with SS-31/Elamipretide (a mitochondria-targeting peptide that reduces oxidative stress and restores mitochondrial membrane potential). Together they address mitochondrial dysfunction from multiple angles, making this a leading longevity and metabolic health protocol.

Half-Life: 2 hours

Common Dosage: 10mg MOTS-c once weekly + 0.5mg SS-31 once daily

Benefits

• Dual mitochondrial support — energy production and oxidative protection
• Improved insulin sensitivity and glucose metabolism (MOTS-c)
• Enhanced cellular energy (ATP) production
• Reduced mitochondrial reactive oxygen species (SS-31)
• Exercise mimetic effects (MOTS-c)
• Potential cardiovascular protection (SS-31)
• Anti-aging at the cellular level
• Improved physical performance and endurance

Side Effects

• Generally well-tolerated
• Mild injection site reactions
• Fatigue on initiation (brief, rare)
• Nausea (rare)
• Headache (rare)