PE-22-28
Category: Cognitive & Nootropic
A spadin analog that acts as a TREK-1 channel blocker. Studied for antidepressant effects and cognitive enhancement with rapid onset of action.
Half-Life: 8 hours
Common Dosage: 50-100mcg
Benefits
- Rapid antidepressant effects
- Cognitive enhancement
- Neurogenesis support
- Improved mood
- Enhanced learning
- Stress resilience
- Does not affect serotonin directly
Side Effects
- Headache
- Mild anxiety initially
- Fatigue
- Sleep changes